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Avocado, Cheese, Grape, Tomato or: How I Used Python to Stop Worrying and Love Emoji in Bioinformatics

Friday 4:20 PM–4:50 PM in Door 12 / Goldfields Theatre

Part of the Scientific Python specialist track

Bioinformatics is the science of understanding and analysing biological information, such as the genetic information contained in DNA. It combines the disciplines of biology, computer science, and mathematics. If this seems daunting, don’t panic, because this talk will focus on two open-source Python packages I have developed, FASTQE and Biomojify, that make common bioinformatics file formats intuitive and accessible…. by using emoji.

FASTQE simplifies DNA sequencing data analysis by taking numerical quality scores for the data, and summarising them using emoji to quickly convey the good, the bad, and the ugly of sequence data quality. Whether for training, outreach, or debugging, this tool can easily turn unremarkable data quality analysis into an appealing visualisation.

Biomojify takes the concept further by converting plain text data to use emoji. In DNA, for example, the conventional format represents individual A, C, G, and T nucleotides as plain text. Biomojify substitutes them with emojis such as avocado, cheese, grape, and tomato. It supports various bioinformatics file formats and supports user defined emoji mapping. It can be used to teach the underlying biological concepts behind bioinformatics data, by simplifying specialised data structures for a general audience.

Science communication is hard. These tools transform complex bioinformatics data into engaging, emoji-based visualisations, making bioinformatics concepts more accessible and adding an element of fun to scientific education and communication.

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This presentation will delve into the history and recent exciting developments of FASTQE and Biomojify. I will provide some background information on bioinformatics, and outline new developments such as support for new sequencing technologies and expanded emoji customization options. I will also present examples of teaching resources developed using these tools.

As a bioinformatician with over a decade of experience and the main developer of these tools, I would love to share my roadmap and encourage more contributors to join these projects. I’m eager to share my love of bioinformatics with the Python community.

Andrew Lonsdale

Andrew had a background in software engineering before deciding to return to study bioinformatics in 2010. After completing the MSc, he was a research assistant and PhD student studying plant cell walls before crossing over to work on human biology in cancer and kidney projects. After submitting his thesis, he began a postdoctoral researcher at the Peter MacCallum Cancer Centre. There he has continued his research interests in the transcriptome of cancers. Andrew is a strong advocate for the discipline of bioinformatics, and enjoys teaching computing and bioinformatics skills.